Protein folding, misfolding, and coping mechanism of cells–A short discussion

K Geetha Roshni*

Proteins are not rigid structures, they are long polypeptide chains of ~50 or more “residues”. Proteins are generally thought to adopt unique structures determined by their amino acid sequences. However, proteins are not strictly static objects, but rather populate ensembles of (sometimes similar) conformations. Transitions between these states occur on a variety of length scales (tenths of Å to nm) and time scales (ns to s), and have been linked to functionally relevant phenomena such as enzyme catalysis [1] and allosteric signaling [2].

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Published on: Jun 21, 2021 Pages: 1-4

Full Text PDF Full Text HTML DOI: 10.17352/ojcps.000003
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