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    CNS-invasive aspergillosis following ibrutinib therapy

    DOI Logo 10.17352/2455-8591.000035

    Published On: December 08, 2022 | Pages: 001 - 003

    Author(s): Matthew Kurian*, Eric Vick and Dipen Khanapara

    ORCID Logo  0000-0003-4015-5261

    Ibrutinib is Bruton’s tyrosine kinase inhibitor that now become the standard of care for the treatment of CLL (chronic lymphocytic leukemia) and other lymphoid cancers. With its increasing usage, oncologists must become more aware of their potential side effect profile. Ibrutinib is typically thought to be less immunosuppressive than standard immunotherapy; however, c ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Supposition about absence of contact inhibition of cancer cells

    DOI Logo 10.17352/2455-8591.000034

    Published On: November 06, 2021 | Pages: 026 - 028

    Author(s): Gogichadze G*, Gogichadze T and Mchedlishvili E
    As is known, the superficial charge of most somatic cells is negative. Proceeding from this fact, somatic cells never interact. There is always some type of space (intercellular space) between them. Intercellular contacts are predominantly determined by two main factors: Van der Waals (positive taxis) and electrostatic (negative taxis) forces contributing to the forma ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    A case of denosumab-associated hyperparathyroidism: A differential diagnostic challenge

    DOI Logo 10.17352/2455-8591.000033

    Published On: October 08, 2021 | Pages: 024 - 025

    Author(s): Emin Taşkıran*, Sevnaz Şahin, Sumru Savaş, Zeliha Fulden Saraç and Selahattin Fehmi Akçiçek
    Denosumab is a relatively new medicine that has become the second option in the treatment of biphosphonate-resistant or intolerant osteoporosis. Subcutaneous injection with 6-month intervals, approval of its usage in stage 3-4 CKD and not having gastrointestinal side effects are advantages of denosumab. However, it has some disadvantages like requiring monitoring seru ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Tumor-associated macrophages: Shifting bad prognosis to improved efficacy in cancer therapies?

    DOI Logo 10.17352/2455-8591.000032

    Published On: May 15, 2021 | Pages: 015 - 023

    Author(s): Guillaume Harlé, Janske Nel, Camille Corbier, Nadège Touche and Stéphanie Grandemange*
    Macrophages are innate immune cells that play an important role in the response to damaged tissue and pathogenic infection. During activation, signals from the local environment induce macrophage polarization towards either the classical pro-inflammatory phenotype (M1) or towards the alternative anti-inflammatory phenotype (M2). In cancer, M2 tumor-associated macropha ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Rosuvastatin inhibit the cell proliferation and the expression of angiogenic factors Vascular Endothelial Growth Factor and Matrix-Metalloproteinase-9 in DU-145 human prostate cancer cells

    DOI Logo 10.17352/2455-8591.000031

    Published On: May 11, 2021 | Pages: 008 - 014

    Author(s): Abdolkhaleg Deezagi*, Armaghan Jamalnia and Hanieh Jaefary
    Abstract Background: Pathophysiology angiogenesis refers to uncontrollable endothelium capillary proliferation, it can be seen in diseases such as growth and metastasis of tumors. The aim of this was to study the effects of Rosuvastatin on the cell growth and expression of the Vascular Endothelial Growth Factor (VEGF) and matrix metal proteases (MMP-9) genes in human ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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